Frank van Leth

Associate Professor Health Sciences

Coverage and yield of tuberculosis contact investigations in the Netherlands.


Journal article


C. Mulder, H. Deutekom, E. Huisman, Wieneke Meijer-Veldman, C. Erkens, J. V. Rest, M. Borgdorff, F. V. Leth
The International Journal of Tuberculosis and Lung Disease, 2011

Semantic Scholar DOI PubMed
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APA   Click to copy
Mulder, C., Deutekom, H., Huisman, E., Meijer-Veldman, W., Erkens, C., Rest, J. V., … Leth, F. V. (2011). Coverage and yield of tuberculosis contact investigations in the Netherlands. The International Journal of Tuberculosis and Lung Disease.


Chicago/Turabian   Click to copy
Mulder, C., H. Deutekom, E. Huisman, Wieneke Meijer-Veldman, C. Erkens, J. V. Rest, M. Borgdorff, and F. V. Leth. “Coverage and Yield of Tuberculosis Contact Investigations in the Netherlands.” The International Journal of Tuberculosis and Lung Disease (2011).


MLA   Click to copy
Mulder, C., et al. “Coverage and Yield of Tuberculosis Contact Investigations in the Netherlands.” The International Journal of Tuberculosis and Lung Disease, 2011.


BibTeX   Click to copy

@article{c2011a,
  title = {Coverage and yield of tuberculosis contact investigations in the Netherlands.},
  year = {2011},
  journal = {The International Journal of Tuberculosis and Lung Disease},
  author = {Mulder, C. and Deutekom, H. and Huisman, E. and Meijer-Veldman, Wieneke and Erkens, C. and Rest, J. V. and Borgdorff, M. and Leth, F. V.}
}

Abstract

SETTING An increasing proportion of tuberculosis (TB) patients in low-incidence countries are immigrants. It is unclear whether contact investigations among immigrant patients are adequate.

OBJECTIVE To determine whether ethnicity of pulmonary TB patients was associated with coverage and yield of contact investigations in the Netherlands.

DESIGN Contact investigation results were extracted from records of patients reported in the nationwide surveillance register in 2006 and 2007. Prevalence odds ratios (PORs) with 95% confidence intervals (CIs) were calculated to determine the association between patient ethnicity and coverage of contact investigations and the yield of individuals with Mycobacterium tuberculosis infection or TB.

RESULTS Of the 1040 pulmonary TB patients reported, 642 (62%) were eligible for analysis. Compared to close contacts of Dutch patients, close contacts of immigrant patients were significantly less likely to be examined for TB (89% vs. 93%, POR 0.6, 95%CI 0.5-0.7) and infection (50% vs. 75%, POR 0.3, 95%CI 0.3-0.4), whereas the yield was significantly higher for disease (1.5% vs. 0.4%, POR 3.4, 95%CI 1.8-6.4) and infection (13% vs. 10%, POR 1.2, 95%CI 1.0-1.5).

CONCLUSION The effectiveness of contact investigations in the Netherlands can be optimised by expanding the investigation of contacts of immigrant patients.


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