Frank van Leth

Associate Professor Health Sciences

Publications


Neighbourhood factors and tuberculosis incidence in Cape Town: A negative binomial regression and spatial analysis


M. Molemans, L. Kayaert, Q. Olislagers, S. Abrahams, N. Berkowitz, E. Mohr-Holland, D. McKelly, R. Wood, F. van Leth, S. Hermans

Tropical medicine & international health, 2024


The plasma kynurenine-to-tryptophan ratio as a biomarker of tuberculosis disease in people living with HIV on antiretroviral therapy: an exploratory nested case–control study


S. Gatechompol, René Lutter, F. M. Vaz, S. Ubolyam, A. Avihingsanon, Stephen J Kerr, F. van Leth, F. Cobelens

BMC Infectious Diseases, 2024


Clinical implications of molecular drug resistance testing for Mycobacterium tuberculosis: a 2023 TBnet/RESIST-TB consensus statement.


J. Domínguez, M. Boeree, E. Cambau, D. Chesov, F. Conradie, V. Cox, K. Dheda, A. Dudnyk, M. Farhat, S. Gagneux, M. Grobusch, M. Gröschel, L. Guglielmetti, I. Kontsevaya, Berit Lange, F. van Leth, C. Lienhardt, A. Mandalakas, F. Maurer, M. Merker, P. Miotto, B. Molina-Moya, Florence Morel, S. Niemann, N. Veziris, A. Whitelaw, C. Horsburgh, C. Lange

Lancet. Infectious Diseases (Print), 2023


Monocyte to lymphocyte ratio and hemoglobin level to predict tuberculosis after antiretroviral therapy initiation


S. Gatechompol, Stephen J. Kerr, S. W. Cardoso, Wadzanai P Samaneka, Srikanth P. Tripathy, S. Godbole, M. Ghate, C. Kanyama, M. Nyirenda, P. Sugandhavesa, Andre Machado, F. van Leth, Thomas B Campbell, Susan Swindlells, A. Avihingsanon, F. Cobelens

AIDS (London), 2023


Predictive performance of interferon-gamma release assays and the tuberculin skin test for incident tuberculosis: an individual participant data meta-analysis


Y. Hamada, Rishi K. Gupta, Matteo Quartagno, Abbie Izzard, C. Acuña-Villaorduña, N. Altet, R. Diel, J. Domínguez, S. Floyd, Amita Gupta, H. Huerga, E. Jones-López, A. Kinikar, C. Lange, F. van Leth, Qiao Liu, Wei Lu, P. Lu, Irene Latorre Rueda, L. Martinez, S. K. Mbandi, L. Muñoz, Elisabeth Sánchez Padilla, Mandar Paradkar, T. Scriba, M. Sester, K. Shanaube, Surendra K Sharma, R. Sloot, G. Sotgiu, K. Thiruvengadam, R. Vashishtha, I. Abubakar, M. Rangaka

EClinicalMedicine, 2023


Reasons for using traditional and complementary care by people living with HIV on antiretroviral therapy and association with interrupted care: a mixed methods study in Eswatini


M. Molemans, Ria Reis, F. Shabalala, Njabuliso Dlamini, Nelisiwe Masilela, Njabulo Simelane, Christopher Pell, Ariel Chao, Donna Spiegelman, E. Vernooij, F. van Leth

BMC Complementary Medicine and Therapies, 2023


Relative cost of multidrug-resistant TB medicines in Europe.


G. Günther, L. Guglielmetti, C. Leu, F. van Leth, C. Lange

The International Journal of Tuberculosis and Lung Disease, 2023


Strengthening primary care for diabetes and hypertension in Eswatini: study protocol for a nationwide cluster-randomized controlled trial


M. Theilmann, Ntombi Ginindza, John Myeni, Sijabulile Dlamini, Bongekile Thobekile Cindzi, D. Dlamini, Thobile L. Dlamini, Maike Greve, Harsh Vivek Harkare, Mbuso Hleta, Philile Khumalo, Lutz Kolbe, S. Lewin, Lisa-Rufaro Marowa, S. Masuku, Dumsile Mavuso, M. Molemans, N. Ntshalintshali, Nomathemba C. Nxumalo, Brianna Osetinsky, C. Pell, R. Reis, F. Shabalala, Bongumusa R. Simelane, Lisa Stehr, F. Tediosi, F. van Leth, Jan‐Walter De Neve, T. Bärnighausen, P. Geldsetzer

Trials, 2023


Availability and costs of medicines for the treatment of tuberculosis in Europe


G. Günther, L. Guglielmetti, C. Leu, C. Lange, F. van Leth, H. Hafizi, N. Khachatryan, Harut Aroyan, E. Kabasakalyan, M. Knappik, A. Skrahina, Dzmitry Klimuk, A. Nikolenka, I. Muylle, Vladimir Milanov, Desislava Velkovska, Neli Tarinska, E. Bachiyska, M. Jankovic, Despo Pieridou, Tonia Adamide, N. Nicolaou, M. Vašáková, Mariia Sukholytka, E. Kopeckà, Å. B. Andersen, D. B. Folkvardsen, E. Svensson, M. Danilovitš, T. Kummik, Tuula Vasankari, M. Fréchet-Jachym, A. Nahmiash, T. Togonidze, Z. Avaliani, Inga Kinkladze, R. Aspindzelashvili, Teona Bichashvili, Gulnazi Losaberidze, Tsitsino Merabishvili, B. Kalsdorf, K. Manika, K. Tsiakitzis, Á. Bakos, Tinna Rán Ægisdóttir, Guðrún Svanhvít Michelsen, Kristín Karlsdóttir, A. McLaughlin, M. Fitzgibbon, D. Chemtob, L. Codecasa, M. Ferrarese, S. Torri, Majlinda Gjocaj, L. Kukša, E. Davidavičienė, G. Wirtz, M. Perrin, Analita Pace Asciak, D. Chesov, W. D. de Lange, O. Akkerman, B. Poposka, Ulrich Mack, M. Jensenius, Lajla Kvalvik, A. Mengshoel, Katarzyna Kruczak, R. Duarte, Nadine Ribeiro, E. Ibraim, A. Kaluzhenina, O. Barkanova, D. Pešut, I. Solovič, P. Svetina, M. D. Souza-Galvão, J. Millet, X. Casas, M. Vives, J. Bruchfeld, Paulina Dalemo, J. Jonsson, Katrin Aeschbacher, Peter Keller, Şeref Özkara, Simon Tiberi, Christabelle Chen, Yana Terleeva, A. Dudnyk

Clinical Microbiology and Infection, 2022


Does distance to healthcare facility affect care-seeking for TB-related symptoms in Tanzania?


S. B. Vergeer, R. Oldenkamp, Mbazi Senkoro, S. Mfinanga, S. Hinderaker, F. van Leth

The International Journal of Tuberculosis and Lung Disease, 2022


Incidence and factors associated with active tuberculosis among people living with HIV after long-term antiretroviral therapy in Thailand: a competing risk model


S. Gatechompol, J. Sophonphan, S. Ubolyam, A. Avihingsanon, F. van Leth, F. Cobelens, S. Kerr

BMC Infectious Diseases, 2022


Neighbourhood risk factors of recurrent tuberculosis in Cape Town: a cohort study using geocoded notification data


M. Molemans, F. van Leth, D. Mckelly, R. Wood, S. Hermans

Journal of Epidemiology and Community Health, 2022


Reasons for, and factors associated with, positive HIV retesting: a cross-sectional study in Eswatini


Quint Olislagers, F. van Leth, F. Shabalala, Njabuliso Dlamini, Njabulo Simelane, Nelisiwe Masilela, G. Gomez, C. Pell, E. Vernooij, R. Reis, M. Molemans

AIDS Care, 2022


Rifapentine access in Europe: growing concerns over key tuberculosis treatment component


L. Guglielmetti, G. Günther, C. Leu, D. Cirillo, R. Duarte, A. García-Basteiro, D. Goletti, M. Jankovic, L. Kukša, F. Maurer, F. Mechaï, Simon Tiberi, F. van Leth, N. Veziris, C. Lange

European Respiratory Journal, 2022


Unbiased antimicrobial resistance prevalence estimates through population-based surveillance.


F. van Leth, C. Schultsz

Clinical Microbiology and Infection, 2022


Antimicrobial resistance among uropathogens in the Asia-Pacific region: a systematic review


A. Sugianli, F. Ginting, I. Parwati, M. D. de Jong, F. van Leth, C. Schultsz

JAC-Antimicrobial Resistance, 2021


Clinical Reasoning Underlying Guideline Nonadherence in Urinary Tract Infections in Nursing Homes.


S. Kuil, F. van Leth, C. Schneeberger, M. D. de Jong, J. Harting

Journal of the American Medical Directors Association, 2021


Defining Outcomes of Tuberculosis (Treatment): From the Past to the Future


G. Günther, J. Heyckendorf, J. Zellweger, M. Reimann, M. Claassens, D. Chesov, F. van Leth

Respiration, 2021


Monocyte-to-lymphocyte ratio as a predictor of TB among people living with HIV.


S. Gatechompol, J. Sophonphan, S. Kerr, S. Ubolyam, A. Avihingsanon, F. van Leth, F. Cobelens

The International Journal of Tuberculosis and Lung Disease, 2021


Prediction of anti-tuberculosis treatment duration based on a 22-gene transcriptomic model


J. Heyckendorf, S. Marwitz, M. Reimann, K. Avsar, A. DiNardo, G. Günther, M. Hoelscher, E. Ibraim, B. Kalsdorf, S. Kaufmann, I. Kontsevaya, F. van Leth, A. Mandalakas, F. Maurer, Marius Müller, Dörte Nitschkowski, I. Olaru, C. Popa, A. Rachow, T. Rolling, J. Rybniker, H. Salzer, Patricia M Sánchez-Carballo, M. Schuhmann, D. Schaub, V. Spînu, I. Suárez, E. Terhalle, M. Unnewehr, J. Weiner, T. Goldmann, C. Lange

European Respiratory Journal, 2021


Use and impact of molecular methods for detecting drug-resistant TB.


B. Molina-Moya, L. Guglielmetti, G. Bothamley, F. van Leth, C. Lange, J. Domínguez

The International Journal of Tuberculosis and Lung Disease, 2021


A 22-gene transcriptomic model indicating individual therapy durations in multidrug-resistant tuberculosis


J. Heyckendorf, S. Marwitz, M. Reimann, K. Avsar, A. DiNardo, G. Günther, M. Hoelscher, E. Ibraim, B. Kalsdorf, S. Kaufmann, I. Kontsevaya, F. V. Leth, A. Mandalakas, F. Maurer, Marius Müller, Dörte Nitschkowski, I. Olaru, C. Popa, A. Rachow, T. Rolling, J. Rybniker, H. Salzer, Patricia M Sánchez-Carballo, M. Schuhmann, D. Schaub, V. Spînu, I. Suárez, E. Terhalle, M. Unnewehr, J. Weiner, T. Goldmann, C. Lange

medRxiv, 2020


Appropriateness of diagnosis and antibiotic use in sepsis patients admitted to a tertiary hospital in Indonesia


F. Ginting, A. Sugianli, M. Barimbing, N. Ginting, Mardianto Mardianto, R. L. Kusumawati, I. Parwati, M. D. de Jong, C. Schultsz, F. van Leth

Postgraduate medicine, 2020


Diapers as Promising Alternative Collection Method for Urine Specimens in Nursing Home Residents: A Noninferiority Study.


S. Kuil, Soemeja Hidad, J. Fischer, C. Visser, F. van Leth, M. D. de Jong, C. Schneeberger

Journal of the American Medical Directors Association, 2020


Discovery and validation of a personalized risk predictor for incident tuberculosis in low transmission settings Authors


Rishi K. Gupta, C. Calderwood, A. Yavlinsky, M. Krutikov, Matteo Quartagno, M. C. Aichelburg, N. Altet, R. Diel, C. Dobler, J. Domínguez, Joseph S. Doyle, C. Erkens, S. Geis, P. Haldar, A. Hauri, Thomas, Hermansen, J. Johnston, C. Lange, B. Lange, F. V. Leth, L. Muñoz, C. Roder, K. Romanowski, D. Roth, M. Sester, Rosa, Sloot, G. Sotgiu, G. Woltmann, T. Yoshiyama, J. Zellweger, D. Zenner, R. Aldridge, A. Copas, M. Rangaka, Marc, Lipman, M. Noursadeghi, I. Abubakar

2020


Laboratory-based versus population-based surveillance of antimicrobial resistance to inform empirical treatment for suspected urinary tract infection in Indonesia


A. Sugianli, F. Ginting, R. L. Kusumawati, I. Parwati, M. D. de Jong, F. van Leth, C. Schultsz

PLoS ONE, 2020


Mass drug administrations with dihydroartemisinin-piperaquine and single low dose primaquine to eliminate Plasmodium falciparum have only a transient impact on Plasmodium vivax: Findings from randomised controlled trials


Koukeo Phommasone, F. van Leth, T. Peto, J. Landier, Thuy-Nhien Nguyen, R. Tripura, T. Pongvongsa, K. Lwin., Ladda Kajeechiwa, May Myo Thwin, D. Parker, Jacher Wiladphaingern, S. Nosten, S. Proux, C. Nguon, Chan Davoeung, H. Rekol, B. Adhikari, Cholrawee Promnarate, K. Chotivanich, B. Hanboonkunupakarn, Podjanee Jittmala, P. Cheah, M. Dhorda, M. Imwong, M. Mukaka, Pimnara Peerawaranun, S. Pukrittayakamee, P. Newton, G. Thwaites, N. Day, M. Mayxay, T. Hien, F. Nosten, F. Cobelens, A. Dondorp, N. White, L. von Seidlein

PLoS ONE, 2020


Sensitivity of C-Reactive Protein and Procalcitonin Measured by Point-of-Care Tests to Diagnose Urinary Tract Infections in Nursing Home Residents: A Cross-Sectional Study


S. Kuil, Soemeja Hidad, J. Fischer, J. Harting, C. Hertogh, J. Prins, M. D. Jong, F. V. Leth, C. Schneeberger

Clinical Infectious Diseases, 2020


The use of ultrasensitive quantitative-PCR to assess the impact of primaquine on asymptomatic relapse of Plasmodium vivax infections: a randomized, controlled trial in Lao PDR


Koukeo Phommasone, F. van Leth, M. Imwong, G. Henriques, T. Pongvongsa, B. Adhikari, T. Peto, Cholrawee Promnarate, M. Dhorda, Pasathorn Sirithiranont, M. Mukaka, Pimnara Peerawaranun, N. Day, F. Cobelens, A. Dondorp, P. Newton, N. White, L. von Seidlein, M. Mayxay

Malaria Journal, 2020


Changes in disclosure, adherence and healthcare interactions after the introduction of immediate ART initiation: an analysis of patient experiences in Swaziland


M. Molemans, E. Vernooij, Njabuliso Dlamini, F. Shabalala, Shaukat Khan, F. van Leth, G. Gomez, R. Reis

Tropical medicine & international health, 2019


Management of patients with multidrug-resistant tuberculosis.


C. Lange, R. Aarnoutse, J. Alffenaar, G. Bothamley, F. Brinkmann, J. Costa, D. Chesov, R. van Crevel, M. Dedicoat, J. Domínguez, R. Duarte, H. Grobbel, G. Günther, L. Guglielmetti, J. Heyckendorf, A. Kay, O. Kirakosyan, O. Kirk, R. Koczulla, G. Kudriashov, L. Kukša, F. van Leth, C. Magis-Escurra, A. Mandalakas, B. Molina-Moya, C. Peloquin, M. Reimann, R. Rumetshofer, H. S. Schaaf, T. Schön, Simon Tiberi, J. Valda, P. Yablonskii, K. Dheda

The International Journal of Tuberculosis and Lung Disease, 2019


Rethinking Antimicrobial Resistance Surveillance: A Role for Lot Quality Assurance Sampling


F. Ginting, A. Sugianli, G. Bijl, Restuti Hidayani Saragih, R. Kusumawati, I. Parwati, M. D. de Jong, C. Schultsz, F. van Leth

American Journal of Epidemiology, 2019


Sensitivity of point-of-care testing C reactive protein and procalcitonin to diagnose urinary tract infections in Dutch nursing homes: PROGRESS study protocol


S. Kuil, Soemeja Hidad, J. Fischer, J. Harting, C. Hertogh, J. Prins, F. van Leth, M. D. de Jong, C. Schneeberger

BMJ Open, 2019


The Tuberculosis Network European Trials group (TBnet) ERS Clinical Research Collaboration: addressing drug-resistant tuberculosis through European cooperation


F. van Leth, F. Brinkmann, D. Cirillo, K. Dheda, R. Duarte, L. Guglielmetti, L. Kukša, C. Lange, C. Mitnick, A. Skrahina, K. Zaman, G. Bothamley

European Respiratory Journal, 2019


Clinical Management of Multidrug‐Resistant Tuberculosis in 16 European Countries


G. Günther, F. van Leth, S. Alexandru, N. Altet, K. Avsar, D. Bang, R. Barbuta, G. Bothamley, A. Ciobanu, V. Crudu, M. Danilovitš, M. Dedicoat, R. Duarte, G. Gualano, H. Kunst, W. D. de Lange, V. Leimane, A. McLaughlin, C. Magis-Escurra, I. Muylle, V. Polcová, C. Popa, R. Rumetshofer, A. Skrahina, V. Solodovnikova, V. Spînu, Simon Tiberi, P. Viiklepp, C. Lange

American Journal of Respiratory and Critical Care Medicine, 2018


Pharmacy-based hypertension care employing mHealth in Lagos, Nigeria – a mixed methods feasibility study


Heleen E. Nelissen, A. Cremers, T. Okwor, Sam Kool, F. van Leth, L. Brewster, Olalekan Makinde, R. Gerrets, M. Hendriks, C. Schultsz, A. Osibogun, A. Van't Hoog

BMC Health Services Research, 2018


Relapse-free cure from multidrug-resistant tuberculosis in Germany


J. Heyckendorf, F. van Leth, B. Kalsdorf, I. Olaru, G. Günther, H. Salzer, E. Terhalle, T. Rolling, G. Glattki, Marius Müller, M. Schuhmann, K. Avsar, C. Lange

European Respiratory Journal, 2018


Testing for LTBI: more of the same or a step forward?


F. van Leth, M. Sester

The International Journal of Tuberculosis and Lung Disease, 2018


Time to revise WHO-recommended definitions of MDR-TB treatment outcomes.


C. Lange, F. van Leth, C. Mitnick, K. Dheda, G. Günther

The Lancet Respiratory Medicine, 2018


Treatment responses in multidrug-resistant tuberculosis in Germany.


J. Heyckendorf, F. van Leth, K. Avsar, G. Glattki, G. Günther, B. Kalsdorf, M. Müller, I. Olaru, T. Rolling, H. Salzer, M. Schuhmann, E. Terhalle, C. Lange

The International Journal of Tuberculosis and Lung Disease, 2018


Antimicrobial resistance in uropathogens and appropriateness of empirical treatment: a population-based surveillance study in Indonesia


A. Sugianli, F. Ginting, R. Kusumawati, Emmy Hermiyati Pranggono, A. Pasaribu, F. Gronthoud, S. Geerlings, I. Parwati, M. D. de Jong, F. van Leth, C. Schultsz

Journal of Antimicrobial Chemotherapy, 2017


Rapid assessment of antimicrobial resistance prevalence using a Lot Quality Assurance sampling approach.


F. van Leth, Casper den Heijer, M. Beerepoot, E. Stobberingh, S. Geerlings, C. Schultsz

Future Microbiology, 2017


Reply: Benefit of the Shorter Multidrug-Resistant Tuberculosis Treatment Regimen in California and Modified Eligibility Criteria.


F. van Leth, G. Günther, H. Hoffmann, C. Lange

American Journal of Respiratory and Critical Care Medicine, 2017


Treatment outcomes of MDR-TB and HIV co-infection in Europe


C. Magis-Escurra, G. Günther, C. Lange, S. Alexandru, N. Altet, K. Avsar, D. Bang, R. Barbuta, G. Bothamley, A. Ciobanu, V. Crudu, Manfred Davilovits, M. Dedicoat, R. Duarte, G. Gualano, H. Kunst, W. D. de Lange, V. Leimane, A. McLaughlin, I. Muylle, V. Polcová, C. Popa, R. Rumetshofer, A. Skrahina, V. Solodovnikova, V. Spînu, Simon Tiberi, P. Viiklepp, F. van Leth

European Respiratory Journal, 2017


Tuberculosis resistance-conferring mutations with fitness cost among HIV-positive individuals in Uganda.


W. Ssengooba, D. Lukoye, C. Meehan, D. Kateete, M. Joloba, B. D. de Jong, F. Cobelens, F. van Leth

The International Journal of Tuberculosis and Lung Disease, 2017


Tuberculosis Treatment Outcomes in Europe: Based on Treatment Completion, Not Cure.


M. Dedicoat, G. Günther, V. Crudu, R. Duarte, G. Gualano, C. Magis-Escurra, R. Rumetshofer, A. Skrahina, V. Spînu, Simon Tiberi, P. Viiklepp, F. van Leth, C. Lange

American Journal of Respiratory and Critical Care Medicine, 2017


Limited Benefit of the New Shorter Multidrug-Resistant Tuberculosis Regimen in Europe.


C. Lange, R. Duarte, M. Fréchet-Jachym, G. Guenther, L. Guglielmetti, I. Olaru, O. Oliveira, R. Rumetshofer, N. Veziris, F. van Leth

American Journal of Respiratory and Critical Care Medicine, 2016


More on Treatment Outcomes in Multidrug-Resistant Tuberculosis.


Christoph Lange, Gunar Günther, F. van Leth

New England Journal of Medicine, 2016


Population impact of factors associated with prevalent pulmonary tuberculosis in Tanzania.


Mbazi Senkoro, A. Kumar, P. Chinnakali, S. Mfinanga, S. Egwaga, V. Kamara, F. van Leth, S. Hinderaker

The International Journal of Tuberculosis and Lung Disease, 2016


Prevalence of pulmonary tuberculosis in adult population of Tanzania: a national survey, 2012.


Mbazi Senkoro, S. Mfinanga, S. Egwaga, R. Mtandu, D. Kamara, D. Basra, L. Fundikira, A. Kahwa, R. Shirima, N. Range, S. Hinderaker, F. van Leth

The International Journal of Tuberculosis and Lung Disease, 2016


Prevention of Early Mortality by Presumptive Tuberculosis Therapy Study: An Open Label, Randomized Controlled Trial.


Y. Manabe, W. Worodria, F. van Leth, H. Mayanja-Kizza, A. Traoré, J. Ferro, N. Pakker, M. Frank, M. Grobusch, R. Colebunders, F. Cobelens

American Journal of Tropical Medicine and Hygiene, 2016


Treatment Outcomes in Multidrug-Resistant Tuberculosis.


G. Günther, C. Lange, S. Alexandru, N. Altet, K. Avsar, D. Bang, R. Barbuta, G. Bothamley, A. Ciobanu, V. Crudu, M. Danilovitš, M. Dedicoat, R. Duarte, G. Gualano, H. Kunst, W. D. de Lange, V. Leimane, C. Magis-Escurra, A. McLaughlin, I. Muylle, V. Polcová, C. Popa, R. Rumetshofer, A. Skrahina, V. Solodovnikova, V. Spînu, Simon Tiberi, P. Viiklepp, F. van Leth

New England Journal of Medicine, 2016


Viral Load and Risk of Tuberculosis in HIV Infection.


C. Lange, F. van Leth, M. Sester

Journal of Acquired Immune Deficiency Syndromes, 2016


Beyond multidrug-resistant tuberculosis in Europe: a TBNET study.


G. Günther, F. van Leth, N. Altet, M. Dedicoat, R. Duarte, G. Gualano, H. Kunst, I. Muylle, V. Spînu, Simon Tiberi, P. Viiklepp, C. Lange

The International Journal of Tuberculosis and Lung Disease, 2015


Factors associated with poor knowledge among adults on tuberculosis in Bangladesh: results from a nationwide survey


Shahed Hossain, K. Zaman, Abdul Quaiyum, S. Banu, Ashaque Husain, A. Islam, M. Borgdorff, F. van Leth

Journal of Health, Population and Nutrition, 2015


Health care-seeking behaviour among people with cough in Tanzania: findings from a tuberculosis prevalence survey.


Mbazi Senkoro, S. Hinderaker, S. Mfinanga, N. Range, D. Kamara, S. Egwaga, F. van Leth

The International Journal of Tuberculosis and Lung Disease, 2015


Implementation of tuberculosis infection prevention and control in Mozambican health care facilities.


Miranda Brouwer, E. Coelho, C. D. D. Mosse, F. V. Leth

The International Journal of Tuberculosis and Lung Disease, 2015


Latent tuberculosis infection as a target for tuberculosis control.


F. van Leth, R. van Crevel, M. Brouwer

Future Microbiology, 2015


Multidrug-Resistant Tuberculosis in Europe, 2010–2011


G. Günther, F. van Leth, S. Alexandru, N. Altet, K. Avsar, D. Bang, R. Barbuta, G. Bothamley, A. Ciobanu, V. Crudu, Manfred Davilovits, M. Dedicoat, R. Duarte, G. Gualano, H. Kunst, W. D. de Lange, V. Leimane, C. Magis-Escurra, A. McLaughlin, I. Muylle, V. Polcová, E. Pontali, C. Popa, R. Rumetshofer, A. Skrahina, V. Solodovnikova, V. Spînu, Simon Tiberi, P. Viiklepp, C. Lange

Emerging Infectious Diseases, 2015


Numbers needed to treat to prevent tuberculosis


M. Sester, R. van Crevel, F. V. Leth, C. Lange

European Respiratory Journal, 2015


TB-HIV co-infection in the Netherlands: estimating prevalence and under-reporting in national registration databases using a capture–recapture analysis


F. van Leth, K. Evenblij, F. Wit, A. Kiers, H. Sprenger, Maurits Verhagen, M. Hillebregt, N. Kalisvaart, H. Schimmel, A. Verbon

Journal of Epidemiology and Community Health, 2015


Antimicrobial drug resistance among clinically relevant bacterial isolates in sub-Saharan Africa: a systematic review.


S. Leopold, F. van Leth, H. Tarekegn, C. Schultsz

Journal of Antimicrobial Chemotherapy, 2014


Antiretroviral therapy and tuberculosis: does the regimen matter?


F. van Leth, F. Wit, S. Hermans

Expert Review of Anti-Infective Therapy, 2014


Availability, price and affordability of anti-tuberculosis drugs in Europe: a TBNET survey


G. Günther, G. Gomez, C. Lange, S. Rupert, F. van Leth

European Respiratory Journal, 2014


Care seeking in tuberculosis: results from a countrywide cluster randomised survey in Bangladesh


Shahed Hossain, K. Zaman, Abdul Quaiyum, S. Banu, Ashaque Husain, A. Islam, M. Borgdorff, F. van Leth

BMJ Open, 2014


Design of pragmatic trials of tuberculosis interventions


F. Cobelens, F. V. Leth, A. V. Hoog

The Lancet, 2014


Embracing the challenges of HIV-TB co-infection in children.


F. van Leth, B. Kampmann

The International Journal of Tuberculosis and Lung Disease, 2014


Healthcare Workers' Challenges in the Implementation of Tuberculosis Infection Prevention and Control Measures in Mozambique


M. Brouwer, E. Coelho, Carla das Dores Mosse, L. Brondi, Laura Winterton, F. van Leth

PLoS ONE, 2014


Management of patients with multidrug-resistant/extensively drug-resistant tuberculosis in Europe: a TBNET consensus statement


C. Lange, I. Abubakar, J. Alffenaar, G. Bothamley, J. Caminero, A. C. Carvalho, K. Chang, L. Codecasa, A. Correia, V. Crudu, P. Davies, M. Dedicoat, F. Drobniewski, R. Duarte, C. Ehlers, C. Erkens, D. Goletti, G. Günther, E. Ibraim, B. Kampmann, L. Kukša, W. D. de Lange, F. van Leth, J. van Lunzen, A. Matteelli, D. Menzies, I. Monedero, E. Richter, S. Rüsch-Gerdes, A. Sandgren, A. Scardigli, A. Skrahina, E. Tortoli, G. Volchenkov, D. Wagner, M. J. van der Werf, B. Williams, W. Yew, J. Zellweger, D. Cirillo

European Respiratory Journal, 2014


Risk assessment of tuberculosis in immunocompromised patients. A TBNET study.


M. Sester, F. van Leth, J. Bruchfeld, D. Bumbăcea, D. Cirillo, A. Dilektaşlı, J. Domínguez, R. Duarte, M. Ernst, F. Eyuboglu, I. Gerogianni, E. Girardi, D. Goletti, J. Janssens, I. Julander, B. Lange, I. Latorre, M. Losi, R. Markova, A. Matteelli, H. Milburn, P. Ravn, T. Scholman, P. Soccal, M. Straub, D. Wagner, T. Wolf, A. Yalçın, C. Lange

American Journal of Respiratory and Critical Care Medicine, 2014


Validation of indirect tuberculosis treatment adherence measures in a resource-constrained setting.


A. Mkopi, N. Range, F. Lwilla, S. Egwaga, Alexander Schulze, E. Geubbels, F. V. Leth

The International Journal of Tuberculosis and Lung Disease, 2014


Are routine tuberculosis programme data suitable to report on antiretroviral therapy use of HIV-infected tuberculosis patients?


M. Brouwer, P. S. Gudo, Chalice Mage Simbe, P. Perdigão, F. van Leth

BMC Research Notes, 2013


Comparison of direct versus concentrated smear microscopy in detection of pulmonary tuberculosis


M. K. M. Uddin, Md. Raihan Chowdhury, Shahriar Ahmed, Md Toufiq Rahman, R. Khatun, F. van Leth, S. Banu

BMC Research Notes, 2013


Entry screening of immigrants in the Netherlands for latent tuberculosis : a cost-effectiveness analysis


C. Mulder, J. Verdier, R. Baltussen, M. Borgdorff, Jan Hendrik, Richardus, F. V. Leth

2013


Epidemiology of Tuberculosis in an Urban Slum of Dhaka City, Bangladesh


S. Banu, Md Toufiq Rahman, M. K. M. Uddin, R. Khatun, T. Ahmed, Md. Mojibur Rahman, M. A. Husain, F. van Leth

PLoS ONE, 2013


Health workers’ performance in the implementation of Patient Centred Tuberculosis Treatment (PCT) strategy under programmatic conditions in Tanzania: a cross sectional study


A. Mkopi, N. Range, M. Amuri, E. Geubbels, F. Lwilla, S. Egwaga, Alexander Schulze, F. van Leth

BMC Health Services Research, 2013


Predictive Value of the Tuberculin Skin Test among Newly Arriving Immigrants


C. Mulder, Brigit Mulleners, M. Borgdorff, F. van Leth

PLoS ONE, 2013


Risk of Tuberculosis after Antiretroviral Treatment Initiation: A Comparison between Efavirenz and Nevirapine Using Inverse Probability Weighting


S. Hermans, Y. Manabe, A. Kiragga, A. Hoepelman, J. Lange, F. van Leth

Antiviral Therapy, 2013


Tuberculin survey in Bangladesh, 2007-2009: prevalence of tuberculous infection and implications for TB control.


Shahed Hossain, K. Zaman, S. Banu, M. Quaiyum, M. Husain, M. A. Islam, E. Cooreman, M. Borgdorff, F. V. Leth

The International Journal of Tuberculosis and Lung Disease, 2013


Adherence by Dutch Public Health Nurses to the National Guidelines for Tuberculosis Contact Investigation


C. Mulder, J. Harting, N. Jansen, M. Borgdorff, F. van Leth

PLoS ONE, 2012


Adherence to Tuberculosis Therapy among Patients Receiving Home-Based Directly Observed Treatment: Evidence from the United Republic of Tanzania


A. Mkopi, N. Range, F. Lwilla, S. Egwaga, Alexander Schulze, E. Geubbels, F. van Leth

PLoS ONE, 2012


Comparison of Macroscopic and Microscopic Assessment of Specimens Collected for the Diagnosis of Tuberculosis


S. Banu, Shahed Hossain, Mohammad Khaja, Mafij Uddin, Md Toufiq Rahman, R. Khatun, K. Zaman, M. Quaiyum, F. van Leth

The Open Infectious Diseases Journal, 2012


Earlier initiation of antiretroviral therapy, increased tuberculosis case finding and reduced mortality in a setting of improved HIV care: a retrospective cohort study


S. Hermans, S. Hermans, S. Hermans, F. V. Leth, Yukari C. Manabe, Yukari C. Manabe, A. Hoepelman, J. Lange, A. Kambugu

HIV Medicine, 2012


Implementation and effect of intensified case finding on diagnosis of tuberculosis in a large urban HIV clinic in Uganda: a retrospective cohort study.


S. Hermans, E. Nasuuna, F. van Leth, Elena Byhoff, M. Schwarz, A. Hoepelman, J. Lange, Y. Manabe

BMC Public Health, 2012


Missed opportunities in tuberculosis control in The Netherlands due to prioritization of contact investigations.


C. Mulder, C. Erkens, P. Kouw, E. Huisman, Wieneke Meijer-Veldman, M. Borgdorff, F. van Leth

European Journal of Public Health, 2012


Multidrug Resistance Among New Tuberculosis Cases: Detecting Local Variation Through Lot Quality-assurance Sampling


B. Hedt, F. van Leth, M. Zignol, F. Cobelens, W. van Gemert, N. V. Nhung, S. Lyepshina, S. Egwaga, T. Cohen

Epidemiology, 2012


Role of the QuantiFERON®-TB Gold In-Tube assay in screening new immigrants for tuberculosis infection


C. Mulder, H. van Deutekom, E. Huisman, S. Toumanian, B. Koster, Wieneke Meijer-Veldman, J. V. van Loenhout-Rooyackers, M. Appel, S. Arend, M. Borgdorff, F. van Leth

European Respiratory Journal, 2012


Socio Economic Position in TB Prevalence and Access to Services: Results from a Population Prevalence Survey and a Facility-Based Survey in Bangladesh


Shahed Hossain, M. Quaiyum, Khalequ Zaman, S. Banu, M. Husain, Mohammad Akramul Islam, Erwin Cooreman, M. Borgdorff, Knut Lönnroth, Abdul Hamid Salim, F. van Leth

PLoS ONE, 2012


The effect of tuberculosis and antiretroviral treatment on CD4+ cell count response in HIV-positive tuberculosis patients in Mozambique


M. Brouwer, Paula Samu Gudo, Chalice Mage Simbe, P. Perdigão, F. van Leth

BMC Public Health, 2012


Unrecognised tuberculosis at antiretroviral therapy initiation is associated with lower CD4+ T cell recovery


S. Hermans, F. van Leth, A. Kiragga, A. Hoepelman, J. Lange, Y. Manabe

Tropical medicine & international health, 2012


Comment on: predictors of immune recovery and the association with late mortality while on antiretroviral treatment in Cambodia.


S. Hermans, S. Hermans, S. Hermans, J. Sempa, B. Castelnuovo, Yukari C. Manabe, Y. Manabe, F. V. Leth

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2011


Contact tracing in low-incidence tuberculosis settings.


F. van Leth, M. Borgdorff

The International Journal of Tuberculosis and Lung Disease, 2011


Coverage and yield of tuberculosis contact investigations in the Netherlands.


C. Mulder, H. Deutekom, E. Huisman, Wieneke Meijer-Veldman, C. Erkens, J. V. Rest, M. Borgdorff, F. V. Leth

The International Journal of Tuberculosis and Lung Disease, 2011


Evaluation of the Genotype® MTBDRplus assay as a tool for drug resistance surveys.


L. Rigouts, A. S. Hoza, P. de Rijk, G. Torrea, T. Chonde, D. Basra, M. Zignol, F. van Leth, S. Egwaga, A. Van Deun

The International Journal of Tuberculosis and Lung Disease, 2011


Guidelines for conducting tuberculin skin test surveys in high-prevalence countries.


H. Rieder, V. Chadha, N. Nagelkerke, F. van Leth, M. J. van der Werf

The International Journal of Tuberculosis and Lung Disease, 2011


Guidelines for conducting tuberculin skin test surveys in high-prevalence countries [Second edition].


H. Rieder, V. Chadha, N. Nagelkerke, F. van Leth, Marieke J vanderWerf

The International Journal of Tuberculosis and Lung Disease, 2011


Health-seeking norms for tuberculosis symptoms in southern Angola: implications for behaviour change communications.


S. Luis, N. Kamp, Ellen M. H. Mitchell, K. Henriksen, F. van Leth

The International Journal of Tuberculosis and Lung Disease, 2011


Highlights of a symposium, Malaria: Where are we today, where are we going?


R. W. Wieten, M. Vugt, F. V. Leth, M. Grobusch

The Open Infectious Diseases Journal, 2011


Incidence and Predictors of Mortality and the Effect of Tuberculosis Immune Reconstitution Inflammatory Syndrome in a Cohort of TB/HIV Patients Commencing Antiretroviral Therapy


W. Worodria, M. Massinga-Loembe, D. Mazakpwe, K. Luzinda, J. Menten, F. van Leth, H. Mayanja-Kizza, L. Kestens, R. Mugerwa, P. Reiss, R. Colebunders

Journal of Acquired Immune Deficiency Syndromes, 2011


Measuring socio-economic data in tuberculosis prevalence surveys.


F. V. Leth, R. Guilatco, Shahed Hossain, A. H. V. Hoog, N. Hoa, M. J. V. D. Werf, Knut Lönnroth

The International Journal of Tuberculosis and Lung Disease, 2011


Prevalence of smear-positive tuberculosis in persons aged ⩾15 years in Bangladesh: results from a national survey, 2007–2009


K. Zaman, Shahed Hossain, S. Banu, M. Quaiyum, P. C. Barua, M. Salim, V. Begum, M. Islam, J. Ahmed, Mahfuza Rifat, E. Cooreman, M. V. D. Werf, M. Borgdorff, F. V. Leth

Epidemiology and Infection, 2011


Risk for progression to tuberculosis among arriving immigrants with a positive IGRA


C. Mulder, H. Deutekom, E. Huisman, S. Toumanian, B. Koster, Wieneke Meijer-Veldman, J. H. V. Loenhout-Rooyackers, M. Appel, S. Arend, C. Erkens, M. Borgdorff, F. V. Leth

European Respiratory journal, 2011


Latent tuberculosis infection and interferon-gamma release assays: what new knowledge did we gain through the Journal in 2009?


M. J. van der Werf, F. van Leth

The International Journal of Tuberculosis and Lung Disease, 2010


National anti-tuberculosis drug resistance study in Tanzania.


T. Chonde, D. Basra, S. Mfinanga, N. Range, F. Lwilla, R. Shirima, A. Deun, M. Zignol, F. Cobelens, S. Egwaga, F. V. Leth

The International Journal of Tuberculosis and Lung Disease, 2010


[Practice guideline prevention, diagnosis and treatment of tuberculosis in patients with an HIV infection].


F. van Leth, Agnes C. Gebhart, R. van Altena, A. Rijkeboer, Annet M Reuskens, P. V. van Gerven

Nederlandsch tijdschrift voor geneeskunde, 2010


The tuberculin skin test: a comparison of ruler and calliper readings.


H. Geldenhuys, S. Verver, S. Surtie, M. Hatherill, F. van Leth, F. Kafaar, M. Tameris, W. Kleynhans, K. K. Luabeya, S. Moyo, W. Sikhondze, W. Hanekom, H. Mahomed

The International Journal of Tuberculosis and Lung Disease, 2010


Annual meeting of the Tuberculosis Surveillance and Research Unit, 2008.


J. Zellweger, S. Verver, S. van den Hof, A. Hesseling, B. Williams, F. van Leth, H. Rieder, M. Borgdorff

The International Journal of Tuberculosis and Lung Disease, 2009


Inclusion of information on risk factors, socio-economic status and health seeking in a tuberculosis prevalence survey.


Knut Lönnroth, Timothy H. Holtz, F. Cobelens, J. Chua, F. V. Leth, T. Tupasi, Bhanu Williams

The International Journal of Tuberculosis and Lung Disease, 2009


Patient-centred tuberculosis treatment delivery under programmatic conditions in Tanzania: a cohort study


S. Egwaga, A. Mkopi, N. Range, Vera Haag-Arbenz, Amuri Baraka, P. Grewal, F. Cobelens, Hassan Mshinda, F. Lwilla, F. van Leth

BMC Medicine, 2009


Projection of the number of patients with tuberculosis in the Netherlands in 2030.


F. van Leth, N. Kalisvaart, C. Erkens, Martien W Borgdoff

European Journal of Public Health, 2009


Assessment of patient preference in allocation and observation of anti-tuberculosis medication in three districts in Tanzania


S. Egwaga, N. Range, F. Lwilla, A. Mkopi, V. Barongo, Sally Mtenga, H. Mshinda, F. Cobelens, Vera Haag, F. van Leth, P. Grewal

Patient Preference and Adherence, 2008


Determination of Clinically Relevant Cutoffs for HIV-1 Phenotypic Resistance Estimates Through a Combined Analysis of Clinical Trial and Cohort Data


B. Winters, J. Montaner, P. Harrigan, B. Gazzard, A. Pozniak, Michael D. Miller, S. Emery, F. van Leth, P. Robinson, J. Baxter, M. Pérez-Elías, D. Castor, S. Hammer, A. Rinehart, H. Vermeiren, E. Van Craenenbroeck, L. Bacheler

Journal of Acquired Immune Deficiency Syndromes, 2008


[Estimation of the incidence of tuberculosis in The Netherlands in 2030].


F. van Leth, N. Kalisvaart, C. Erkens, M. Borgdorff

Nederlandsch tijdschrift voor geneeskunde, 2008


Implementation of a national anti-tuberculosis drug resistance survey in Tanzania


T. Chonde, B. Doulla, F. van Leth, S. Mfinanga, N. Range, F. Lwilla, S. Mfaume, A. Van Deun, M. Zignol, F. Cobelens, S. Egwaga

BMC Public Health, 2008


Measuring tuberculosis burden, trends, and the impact of control programmes.


C. Dye, A. Bassili, A. Bierrenbach, J. Broekmans, V. Chadha, P. Glaziou, P. G. Gopi, Mehran Hosseini, Kim Sj, D. Manissero, I. Onozaki, H. Rieder, Suzanne Scheele, F. V. Leth, M. V. D. Werf, Brett Williams

Lancet. Infectious Diseases (Print), 2008


Organisation of a tuberculosis prevalence survey.


F. V. Leth, F. Cobelens, Ikushi Onozaki

The International Journal of Tuberculosis and Lung Disease, 2008


Prevalence of tuberculous infection and incidence of tuberculosis: a re-assessment of the Styblo rule.


F. V. Leth, M. V. D. Werf, M. Borgdorff

Bulletin of the World Health Organization, 2008


Risk Factors for Smear Negative And Culture Positive Results Among Pulmonary Tuberculosis Patients in Mwanza, Tanzania


Å. B. Andersen, F. V. Leth, P. Magnussen, Mugomela Apolinary, H. Friis, M. Tanzania

The Open Tropical Medicine Journal, 2008


Tuberculosis prevalence surveys: rationale and cost.


P. Glaziou, M. J. V. D. Werf, Ikushi Onozaki, Christopher Dye, M. Borgdorff, Chiang Yuan Chen, F. Cobelens, D. Enarson, P. G. Gopi, Timothy H. Holtz, Kim Sj, F. V. Leth, W. J. Lew, Knut Lönnroth, P. V. Maaren, P. R. Narayanan, Bhanu Williams

The International Journal of Tuberculosis and Lung Disease, 2008


Methodological standards in non-inferiority AIDS trials: moving from adherence to compliance: Response


Frank van Leth, Ferdinand W Wit, Joep M. A. Lange

BMC Medical Research Methodology, 2007


Epstein-Barr virus infects B and non-B lymphocytes in HIV-1-infected children and adolescents.


V. Bekker, H. Scherpbier, M. Beld, E. Piriou, A. van Breda, J. Lange, F. van Leth, S. Jurriaans, Sophie Alders, P. W. Wertheim-van Dillen, D. van Baarle, T. Kuijpers

Journal of Infectious Diseases, 2006


Long-term Experience With Combination Antiretroviral Therapy That Contains Nelfinavir for up to 7 Years in a Pediatric Cohort


H. Scherpbier, V. Bekker, F. van Leth, S. Jurriaans, J. Lange, T. Kuijpers

Pediatrics, 2006


Are Adverse Events of Nevirapine and Efavirenz Related to Plasma Concentrations?


B. Kappelhoff, F. van Leth, P. Robinson, T. Macgregor, E. Baraldi, F. Montella, D. Uip, M. Thompson, D. Russell, J. Lange, J. Beijnen, A. Huitema

Antiviral Therapy, 2005


Cytomegalovirus rather than HIV triggers the outgrowth of effector CD8+CD45RA+CD27− T cells in HIV-1-infected children


V. Bekker, C. Bronke, H. Scherpbier, J. Weel, S. Jurriaans, P. W. Wertheim-van Dillen, F. V. Leth, J. Lange, K. Tesselaar, D. Baarle, T. Kuijpers

AIDS (London), 2005


Nevirapine and Efavirenz Pharmacokinetics and Covariate Analysis in the 2Nn Study


B. Kappelhoff, F. van Leth, T. Macgregor, J. Lange, J. Beijnen, A. Huitema

Antiviral Therapy, 2005


Pharmacokinetics of Nevirapine: Once-Daily Versus Twice-Daily Dosing in the 2NN Study


B. Kappelhoff, A. Huitema, F. van Leth, P. Robinson, T. Macgregor, J. Lange, J. Beijnen

HIV Clinical Trials, 2005


Plasma HIV-1 RNA Decline Within the First Two Weeks of Treatment Is Comparable for Nevirapine, Efavirenz, or Both Drugs Combined and Is Not Predictive of Long-Term Virologic Efficacy: A 2NN Substudy


F. van Leth, Casper B Huisamen, R. Badaró, B. Vandercam, J. de Wet, J. Montaner, D. Hall, F. Wit, J. Lange

Journal of Acquired Immune Deficiency Syndromes, 2005


Comparison of first-line antiretroviral therapy with regimens including nevirapine, efavirenz, or both drugs, plus stavudine and lamivudine: a randomised open-label trial, the 2NN Study


F. V. Leth, P. Phanuphak, K. Ruxrungtham, E. Baraldi, S. Miller, B. Gazzard, P. Cahn, U. Lalloo, IP van der Westhuizen, Malan, Margaret A. Johnson, B. Santos, F. Mulcahy, R. Wood, GC Levi, G. Reboredo, K. Squires, I. Cassetti, D. Petit, F. Raffi, C. Katlama, R. Murphy, A. Horban, JP Dam, E. Hassink, R. V. Leeuwen, P. Robinson, F. Wit, J. Lange

The Lancet, 2004


Differential CD4 T‐cell response in HIV‐1‐infected patients using protease inhibitor‐based or nevirapine‐based highly active antiretroviral therapy


F. van Leth, F. Wit, P. Reiss, J. Schattenkerk, M. Van Der Ende, Mme Schneider, J. Mulder, P. Frissen, F. de Wolf, J. Lange

HIV Medicine, 2004


Highly active antiretroviral therapy with or without mycophenolate mofetil in treatment-naive HIV-1 patients


S. Sankatsing, S. Jurriaans, P. van Swieten, F. van Leth, M. Cornelissen, F. Miedema, J. Lange, H. Schuitemaker, J. Prins

AIDS (London), 2004


Lipid profiles in HIV-1-infected individuals receiving combination antiretroviral therapy: are different protease inhibitors or non-nucleoside reverse transcriptase inhibitors associated with different lipid profiles?


E. Fontas, F. V. Leth, C. Sabin, N. Friis‐Møller, M. Rickenbach, A. Monforte, O. Kirk, M. Dupon, L. Morfeldt, S. Mateu, K. Petoumenos, W. El-Sadr, S. Wit, J. Lundgren, C. Pradier, P. Reiss

The Journal of Infectious Diseases, 2004


Nevirapine and Efavirenz Elicit Different Changes in Lipid Profiles in Antiretroviral- Therapy-Naive Patients Infected with HIV-1


F. van Leth, P. Phanuphak, E. Stroes, B. Gazzard, P. Cahn, F. Raffi, R. Wood, M. Bloch, C. Katlama, J. Kastelein, M. Schechter, R. Murphy, A. Horban, D. Hall, J. Lange, P. Reiss

PLoS Medicine, 2004


Quality of Life in Patients Treated with First-Line Antiretroviral Therapy Containing Nevirapine And/Or Efavirenz


F. van Leth, B. Conway, H. Laplumé, Des Martin, M. Fisher, A. Jelaska, F. Wit, J. Lange

Antiviral Therapy, 2004


A randomized trial to study first-line combination therapy with or without a protease inhibitor in HIV-1-infected patients


R. van Leeuwen, C. Katlama, R. Murphy, K. Squires, J. Gatell, A. Horban, B. Clotet, S. Staszewski, A. van Eeden, N. Clumeck, M. Moroni, A. Pavia, R. Schmidt, J. González-Lahoz, J. Montaner, F. Antunes, R. Gulick, D. Bánhegyi, M. van der Valk, P. Reiss, Liesbeth van Weert, F. van Leth, V. Johnson, J. Sommadossi, J. Lange

AIDS (London), 2003


Identifying malnourished children may not be easy


F. van Leth

British medical journal, 2003


Use of composite end points to measure clinical events.


F. van Leth, J. Lange

Journal of the American Medical Association (JAMA), 2003


Highly active antiretroviral therapy-induced lipodystrophy has minor effects on human immunodeficiency virus-induced changes in lipolysis, but normalizes resting energy expenditure.


M. van der Valk, P. Reiss, F. van Leth, M. Ackermans, E. Endert, J. Romijn, R. Heijligenberg, H. Sauerwein

Journal of Clinical Endocrinology and Metabolism, 2002


Nevirapine-containing antiretroviral therapy in HIV-1 infected patients results in an anti-atherogenic lipid profile


M. van der Valk, J. Kastelein, R. Murphy, F. van Leth, C. Katlama, A. Horban, M. Glesby, G. Behrens, B. Clotet, R. Stellato, H. Molhuizen, P. Reiss

AIDS (London), 2001


Malnutrition: more than the eye can see


F.C. van Leth, J.M. Koeleman, A.S. Manya

East Afr Med J, vol. 77, 2000 Oct, pp. 549--51

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